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NewsFox 13 News (WTVT) — All NewsAugust 28, 2026Hillsborough

FDA approves updated COVID-19 vaccines targeting XFG 'Stratus' variant

The FDA has approved updated COVID-19 vaccines from Moderna, Novavax-Sanofi, and Pfizer-BioNTech for the 2026-27 immunization season. These new doses are specifically formulated to target the XFG 'Stratus' variant, which currently accounts for approximately 79% of U.S. COVID-19 cases.

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Why It Matters

Residents will have access to updated vaccines designed to combat the dominant XFG variant during the 2026-27 season, which health officials recommend as a tool to mitigate the spread of the virus.

Key Facts

  • The FDA approved updated COVID-19 vaccines for the 2026-27 season from Moderna, Novavax-Sanofi, and Pfizer-BioNTech.
  • The new vaccines are specifically designed to target the XFG variant, also known as 'Stratus'.
  • The XFG variant accounted for an estimated 79% of U.S. COVID-19 cases for the week ending September 6.
  • Moderna and Pfizer-BioNTech vaccines utilize mRNA technology.
  • The Novavax-Sanofi vaccine is protein-based.
  • The FDA advisory committee voted 8-1 in May to select the XFG variant for the upcoming campaign.
  • The previous 2025-26 vaccine season targeted the LP.8.1 subvariant.
  • The XFG variant originated in Southeast Asia in January and reached the U.S. in the spring.

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