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NewsKQED News — San Francisco tagOctober 23, 2026San Francisco County

San Francisco Reports 48 Overdoses in September, Including First Death Linked to Synthetic Opioid MGM-15

Photo: KQED News — San Francisco tag

San Francisco health officials reported 48 fatal drug overdoses in September, bringing the city's total accidental overdose deaths this year to 399, and announced the city's first fatal overdose involving a synthetic opioid called MGM-15 sold in convenience stores.

Read the full story at KQED News — San Francisco tag

Why It Matters

The disclosure highlights the emergence of a new synthetic opioid sold in retail stores under misleading herbal supplement packaging, with health officials advising the use of for suspected overdoses.

Key Facts

  • San Francisco recorded 48 fatal drug overdoses in September, bringing the year's total to 399.
  • The city recorded its first fatal overdose from the synthetic opioid MGM-15, which was sold at gas stations and convenience stores.
  • MGM-15 is a kratom-derived opioid that produces more potent effects than morphine and can cause physical and psychological dependence.
  • The pill's packaging was marketed as a 'paradise blend' of 'uncaria tomentosa extract' (cat's claw) and did not mention kratom or MGM-15.
  • The Drug Enforcement Agency has labeled MGM-15 as a schedule-1 controlled substance.
  • Officials in Utah and Washington have previously identified overdose deaths from MGM-15 in their states.
  • Health officials state that anyone believed to be suffering an overdose from MGM-15 should be given naloxone (Narcan).
  • The majority of individuals who died in September were white men.
  • Nearly half of the September deaths occurred in ZIP codes including the Tenderloin, Civic Center, and Mid-Market neighborhoods.
  • Overdose deaths have fallen in recent years in San Francisco but remain higher than pre-pandemic levels.

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